OttoPure
Protein Purification System
The OttoPure is an efficient and high-throughput system for up to 40X faster than manual protein purification.
Efficient automation for diverse bio-purification needs
The OttoPure is a powerful and versatile automated system designed to streamline your protein purification workflow. Capable of processing samples ranging from 1 mL to 1 L, it eliminates the labor-intensive steps associated with manual purification.
Utilizing positive pressure technology, the OttoPure ensures consistent flow rates and precise fluid delivery, preventing column clogging and ensuring all samples finish simultaneously. It is the ideal choice for laboratories seeking to scale up their purification of antibodies, enzymes, antigens, and other biomolecules.
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Automated Protein Purification System
OttoPure
The OttoPure system has been developed to provide a fully automated and standardized solution for high-throughput protein purification. Designed for efficiency and simplicity, it processes up to 8 samples simultaneously, delivering results up to 40 times faster than manual methods.
Product Details
The system’s flow path is constructed from highly inert and corrosion-resistant materials, making it compatible with biological samples as well as various acids, bases, and salts. Its compact footprint allows it to fit easily on a benchtop or inside a refrigerator/cold room.
Compatible with biological samples, acids, bases, and salts
For proteins such as enzymes and antigens that require low-temperature preservation
Saves up to 100 methods for automated protein purification, system cleaning, and column regeneration
- Online resin cleaning and re-equilibration and optional strip/re-charge
- Supports multiple purification cycles with reduced consumables and waste
- Integrated touchscreen with UV trace visualization
- No external PC required
- Small bench-top footprint
- Cold-room / cabinet compatible
LUMERA Applications: What Can You Purify?
Antibody Purification
LUMERA supports Protein A, Protein G, and Protein L affinity purification of monoclonal antibodies, polyclonal antibodies, and antibody fragments. Purify up to 8 antibody batches in parallel -- ideal for early-stage screening and clone selection workflows.
IMAC / His-Tag Protein Purification
Run parallel IMAC purifications of His-tagged recombinant proteins across 8 channels simultaneously using Ni-NTA, Co-NTA, or Cu-NTA resins. LUMERA's automated flow-through re-application recovers unbound His-tagged protein missed in a standard single-pass workflow.
Ion Exchange & Hydrophobic Interaction Chromatography
LUMERA is compatible with cation exchange (CEX), anion exchange (AEX), and hydrophobic interaction chromatography (HIC) resins from all major manufacturers. Use LUMERA for polishing steps, charge-variant screening, or high-throughput method development across multiple conditions in one run.
Oligonucleotide & Small Biomolecule Purification
Beyond proteins, LUMERA supports purification of oligonucleotides, metabolites, and other biomolecules using standard SPE cartridge formats -- extending the instrument's utility across a broader range of lab workflows.
Consumables for OttoPure system
Extensive Column Compatibility
with columns from 1mL to 70mL, including GE HiTrap™, gravity-flow columns, and standard SPE cartridges, supporting a wide range of affinity, ion exchange, hydrophobic interaction, and other applications.
