LUMERA™
Illuminating a New Era of Protein Purification
High-throughput. High Protein Yield. Simplicity. Purify up to 8 samples in parallel with real-time UV detection, up to 40X faster than manual protein purification.
Scale Your Throughput Without Scaling Headcount
LUMERA™ is an advanced automated protein purification system engineered for biotechnology, pharmaceutical, academic, and government research laboratories. Unlike traditional single-channel FPLC systems, LUMERA processes up to 8 protein samples simultaneously using positive-pressure liquid delivery for consistent, synchronized results. Integrated real-time UV detection at 280 nm provides live visibility into column loading, breakthrough, and elution phases, eliminating manual sampling and guesswork. LUMERA's automated flow-through re-application - a capability unique to this platform that recovers unbound target protein and maximizes resin utilization, significantly improving overall protein yield compared to a standard gravity-column or FPLC workflow.
The system supports up to 9 buffer solutions and is fully compatible with pre-packed columns (including GE HiTrap™), self-poured columns, gravity-flow columns, and standard SPE cartridges. Whether you are running affinity, IMAC/His-tag purification, ion exchange chromatography (IEX), or hydrophobic interaction chromatography (HIC), LUMERA represents a step-change in daily laboratory output without requiring additional instrument overhead or operator time.
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Automated Protein Purification System
LUMERA
The LUMERA system has been developed to provide a fully automated and standardized solution for high-throughput protein purification. Designed for efficiency and simplicity, it processes up to 8 samples simultaneously, delivering results up to 40 times faster than manual methods.
Product Details
LUMERA™ is an advanced automated protein purification system engineered for biotechnology, pharmaceutical, academic, and government research laboratories. Unlike traditional single-channel FPLC systems, LUMERA processes up to 8 protein samples simultaneously using positive-pressure liquid delivery for consistent, synchronized results.
The system supports up to 9 buffer solutions and is fully compatible with pre-packed columns (including GE HiTrap™), self-poured columns, gravity-flow columns, and standard SPE cartridges. From antibody purification and IMAC/His-tag purification to ion exchange chromatography (IEX) and hydrophobic interaction chromatography (HIC), LUMERA™ delivers a massive boost to your daily laboratory output. It maximizes your processing capabilities and efficiency without the need for additional instruments or increased operator involvement.
LUMERA processes up to 8 protein samples simultaneously, each up to 1 litre, in a single unattended run. This represents a step-change in daily output without additional instrument overhead or operator time.
Integrated UV monitoring at 280 nm delivers live visibility into every stage of the purification: column loading, breakthrough point, and peak elution. Unlike systems that require manual fraction sampling after the run, LUMERA lets researchers make data-driven decisions in real time and reduce post-run analysis time.
LUMERA's automated flow-through re-application recovers unbound target protein that would be lost in a standard bind-and-elute workflow. By automatically re-applying flow-through fractions, LUMERA maximizes resin utilization and overall yield, particularly valuable when working with low-expression constructs or expensive affinity resins.
- Online resin cleaning and re-equilibration and optional strip/re-charge
- Supports multiple purification cycles with reduced consumables and waste
- Integrated touchscreen with UV trace visualization
- No external PC required
- Small bench-top footprint
- Cold-room / cabinet compatible
LUMERA Applications: What Can You Purify?
Antibody Purification
LUMERA supports Protein A, Protein G, and Protein L affinity purification of monoclonal antibodies, polyclonal antibodies, and antibody fragments. Purify up to 8 antibody batches in parallel -- ideal for early-stage screening and clone selection workflows.
IMAC / His-Tag Protein Purification
Run parallel IMAC purifications of His-tagged recombinant proteins across 8 channels simultaneously using Ni-NTA, Co-NTA, or Cu-NTA resins. LUMERA's automated flow-through re-application recovers unbound His-tagged protein missed in a standard single-pass workflow.
Ion Exchange (IEX) & Hydrophobic Interaction Chromatography (HIC)
LUMERA is compatible with cation exchange (CEX), anion exchange (AEX), and hydrophobic interaction chromatography (HIC) resins from all major manufacturers. Use LUMERA for polishing steps, charge-variant screening, or high-throughput method development across multiple conditions in one run.
Oligonucleotide & Small Biomolecule Purification
Beyond proteins, LUMERA supports purification of oligonucleotides, metabolites, and other biomolecules using standard SPE cartridge formats -- extending the instrument's utility across a broader range of lab workflows.
Consumables for LUMERA System
Extensive Column Compatibility
with Pre-packed columns (GE HiTrap™) and Self-packed columns, gravity-flow columns, and standard SPE cartridges, supporting a wide range of affinity, ion exchange, hydrophobic interaction and other applications.
Request a quote
Investing in the LUMERA protein purification system is a pivotal step toward enhancing your laboratory's efficiency, reproducibility, and overall performance. With its advanced capabilities, including real-time UV detection and automated flow-through re-application, our purification platforms empower your team to streamline complex workflows, eliminate manual guesswork, and maximize protein yields critical for downstream success. Experience the transformative impact our products can bring to your operations. Reach out to us for a custom quote.
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